RESUMO
During 2018-2020, we isolated 32 Eurasian avian-like swine influenza A(H1N1) viruses and their reassortant viruses from pigs in China. Genomic testing identified a novel reassortant H3N1 virus, which emerged in late 2020. Derived from G4 Eurasian H1N1 and H3N2 swine influenza viruses. This virus poses a risk for zoonotic infection.
Assuntos
Vírus da Influenza A Subtipo H1N1 , Influenza Humana , Infecções por Orthomyxoviridae , Doenças dos Suínos , Animais , Aves , Humanos , Vírus da Influenza A Subtipo H1N1/genética , Vírus da Influenza A Subtipo H3N2/genética , Vírus da Influenza A , Influenza Humana/epidemiologia , Infecções por Orthomyxoviridae/epidemiologia , Infecções por Orthomyxoviridae/veterinária , Filogenia , Vírus Reordenados/genética , Suínos , Doenças dos Suínos/epidemiologiaRESUMO
To optimize the one-step pelletization technology of Fuke IV (FKIV) granules by response surface methodology. With the qualified rate of granules as evaluation indexes, 6 factors affecting one-step pelletization technology were investigated, significant levels of each factor were evaluated and the primal influential factors were determined by Plackett-Burman experimental design. According to the Plackett-Burman experimental design, the qualified rates of granules, moisture capacity and angle of repose as the evaluation indexes, Box-Behnken design with three levels and three factors was established for quadratic regression fitting of the models. Then the experimental results were optimized by Response Optimizer. The best process conditions were determined as followsï¼ the extract relative density of 1.20, inlet air temperature of 88 â, and atomization pressure of 0.28 MPa. FKIV granules were prepared by the optimized experimental scheme. The determined qualified rate, moisture capacity and angle of response were 93.65%, 3.76% and 23.19° respectively for the granules, basically similar to the predicted values, indicating that the optimal process conditions were in line with the manufacturing requirements.
Assuntos
Composição de Medicamentos/métodos , Medicamentos de Ervas Chinesas/química , Composição de Medicamentos/instrumentação , Projetos de Pesquisa , TemperaturaRESUMO
The laser-induced breakdown spectroscopy (LIBS) technique, due to its lack of pretreatment of the material and the speed of analysis, has shown a great potential for a wide range of industrial applications. The current situation of application and study of LIBS are reviewed. Meanwhile, the laser used to explode the Cr and Co film had a pulse duration of 10 ns, the highest single pulse energy was 50 mJ at a repetition rate of 20 Hz, and a wavelength of 1064 nm. When the excitation energy was less than 10 mJ, there was little difference in spectral signal excited by different energy for Cr film. Otherwise, the signal showed obvious change when excitation energy was higher than 10 mJ. The principle, characters, history and recent trend of LIBS were introduced systematically. The factors influencing LIBS performances, including the characteristic of laser, delay time, experiment setting, the kind and the pressure of surrounding. Gas, single or dual pulse, and the analysis method were analyzed.
